28. October 2015 - Institut Laue-Langevin
Research Scientist in Macromolecular Crystallography
Research Scientist in Macromolecular Crystallography
28. October 2015 - Institut Laue-Langevin
Research Scientist in Macromolecular Crystallography
Research Scientist in Macromolecular Crystallography
Institut Laue-Langevin

ILL, Grenoble, FRANCE

Description of Institution

The Institut Laue-Langevin (ILL), situated in Grenoble, France, is Europe’s leading research facility for scientific research using neutrons. The ILL operates the brightest neutron source in the world, reliably delivering intense neutron beams to 40 unique scientific instruments. We welcome more than 2000 visiting scientists per year to carry out world-class research.

Job description

The LSS group comprises a range of instruments designed to carry out studies on the structure of matter on a scale of one to hundreds of nanometres. These include instruments for small-angle scattering, reflectometry, diffraction from single crystals or one or two-dimensionally ordered materials. The range of science covered is very broad, from polymer and colloid science through structural molecular biology to materials science and magnetic phenomena.

Working within the LSS Group in the field of Macromolecular Crystallography (MX), in addition to carrying out your own active research programme, you will be in charge of:

  • co-managing the LADI-III diffractometer, participating both in the day-to-day running of the instrument and its technical development,
  • providing support to users for scientific experiments on the LADI-III diffractometer and helping them collect data under optimum conditions,
  • promoting scientific partnerships in your field of research,
  • participating in the longer term development of new instrumentation for MX using neutrons (as part of the Endurance programme).

The LADI-III instrument is a quasi-Laue diffractometer dedicated to high-resolution crystallographic studies of biological macromolecules in order to locate H-atoms of special interest, providing information on protonation states, H-bonding and water molecule orientations that can be critical for understanding macromolecular function and behaviour.

Requested Profile

Qualifications and experience:
PhD in physics, biophysics or chemistry.
We are particularly interested in highly motivated candidates with experience in macromolecular crystallography and structural biology willing to carry out a personal research programme and contribute to the scientific environment in life sciences areas at the ILL.
Good computing skills and a general interest in software development would be an advantage, as would experience in physical measurements of biological systems.

The post represents an excellent opportunity for young postdoctoral scientists to develop expertise, broaden their experience and interact with leading scientists from around the world. Applications from more experienced scientists able to obtain a secondment period from their home institution will also be considered.

Language skills:
As an international research centre, we are particularly keen to ensure that we also attract applicants from outside France. You must have a sound knowledge of English and be willing to learn French (a language course will be paid for by the ILL). Knowledge of German would be an advantage.


Dr. Matthew Blakeley and Dr. Giovanna Fragneto

How to Apply

Please submit your application with a list of publications and the name of 3 references (including one from your present work place) on-line, no later than 29/11/2015, via our web site: http://www.ill.eu/careers (vacancy reference: 15/19). The interviews will take place the first week of January 2016.

5-year fixed-term contract
Further information can be obtained by contacting the LADI-III responsible: Dr. Matthew Blakeley, , +33(0), or the head of the Large Scale Structures (LSS) Group: Dr. Giovanna Fragneto, , +33(0) or via http://www.ill.fr/lss.

Generous company benefits (expatriation allowance), relocation assistance and language courses may be offered for you and your spouse (for more information, please consult our employment conditions).

29. November 2015
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