24. March 2016 - Oak Ridge National Laboratory (ORNL)
Postdoctoral Research Associate - Protein Chemist/Structural Biologist
ORNL: Postdoctoral Research Associate - Protein Chemist/Structural Biologist / NB50554699
24. March 2016 - Oak Ridge National Laboratory (ORNL)
Postdoctoral Research Associate - Protein Chemist/Structural Biologist
ORNL: Postdoctoral Research Associate - Protein Chemist/Structural Biologist / NB50554699
Employer
Oak Ridge National Laboratory (ORNL)
Location

Oak Ridge, USA

Description of Institution

The Neutron Sciences Directorate (NScD) at Oak Ridge National Laboratory (ORNL) operates the High Flux Isotope Reactor (HFIR), the United States’ highest flux reactor based neutron source, and the Spallation Neutron Source (SNS), the world’s most intense pulsed accelerator based neutron source. Together these facilities operate 30 instruments for neutron scattering research, each year carrying out in excess of 1,000 experiments in the physical, chemical, materials, biological and medical sciences. HFIR also provides unique facilities for isotope production and neutron irradiation.
To learn more about Neutron Sciences at ORNL go to: http://neutrons.ornl.gov.

Job description

Purpose:

The Biology and Soft Matter Division at Oak Ridge National Laboratory (ORNL) invites applications for a post-doctoral structural biologist or macromolecular crystallographer to join its Biology and Biomedical Science group. The successful candidate will join a multi-disciplinary research team investigating the structure and function of biological complexes that are involved in cell-signaling, DNA repair and light harvesting systems. These projects involve multi-task efforts in molecular biology, protein crystallography, small–angle scattering and computational modeling. The position represents an excellent opportunity for researchers to develop their careers and interact with leading scientists from around the world. As an ORNL postdoctoral fellow you will have access to leading small angle scattering and neutron diffraction facilities, biofermentation laboratories, and biophysical characterization laboratories, in addition to in-house small angle X-ray scattering and X-ray diffraction instrumentation. The position represents an excellent opportunity for researchers to develop their careers and interact with leading scientists from around the world.

Major Duties/Responsibilities:

Responsible for protein labeling, purification, crystallization and X-ray and neutron crystallographic studies.

  • Assist in optimization of labeling strategies for proton polarization and analysis.
  • Publish scientific papers on this collaborative research
  • Present scientific results at appropriate national and international conferences
  • Ensure compliance with environment, safety, health and quality program requirements.
  • Maintain strong commitment to the implementation and perpetuation of values and ethics.
  • Physical requirements for this job include the use of hand and eye protection gear, kneeling, sitting for extended periods of
    time, extensive work at chemical laboratories, and possible exposure to ionization radiation normally associated with operation of neutron scattering instruments for scientific research.

Requested Profile

Qualifications Required:

A Ph.D. degree in protein chemistry, biophysics or structural biology is required. The candidates should have a proven track record in molecular biology techniques including cloning, protein expression and purification, and in biophysical characterization using NMR/EPR or X-ray techniques. The candidate should be self-motivated, have excellent interpersonal, communication and presentational skills and a demonstrated ability to interact effectively with staff at all levels within a
multi-disciplinary team.

Applicants must have received their PhD within five years of this application and must complete all degree requirements before starting their appointment.
Employment is contingent upon the results of a pre-employment drug screen which must be administered and cleared before employment can begin.

Qualifications Desired:

Additional experience in expression and production of membrane proteins or in covalent modification of proteins with fluorophores or spin labels, would be a distinct advantage.

Contact
How to Apply

Go to https://www.ornl.gov/careers .

This position will remain open for a minimum of 5 days after which it will close when a qualified candidate is identified and/or hired.

We accept Word(.doc, .docx), Excel(.xls, .xlsx), PowerPoint(.ppt, .pptx), Adobe(.pdf), Rich Text Format(.rtf), HTML and text files(.txt) up to 2MB in size. Resumes from third party vendors will not be accepted; these resumes will be deleted and the candidates submitted will not be considered for employment.

If you have trouble applying for a position, please email ORNLR@ornl.gov.

Deadline
22. April 2016
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