07. February 2017 - University of Oslo
PhD Research Fellowship in Biological Soft Matter - “Mechanism of Antimicrobial Peptides seen by Neutron Scattering”
University of Oslo: PhD Research Fellowship in Biological Soft Matter - “Mechanism of Antimicrobial Peptides seen by Neutron Scattering”
07. February 2017 - University of Oslo
PhD Research Fellowship in Biological Soft Matter - “Mechanism of Antimicrobial Peptides seen by Neutron Scattering”
University of Oslo: PhD Research Fellowship in Biological Soft Matter - “Mechanism of Antimicrobial Peptides seen by Neutron Scattering”
Employer
University of Oslo
Location

Oslo, Norway

Introduction

Position as PhD Research fellow available at the Department of Chemistry – University of Oslo for three years.

Job description

Job/ project description:

We offer a PhD position in Biological Soft Matter/Physical Chemistry in the Soft Matter group of Reidar Lund at the Department of Chemistry, University of Oslo.

Antimicrobial peptides and peptoidomimetic compounds such as peptoids, are promising candidates to fight resistant bacteria. However, their mechanism is not understood in detail and issues such as toxicity and sensitivity towards proteolytic degradation limit their practical applications. The project aims to understand the fundamental biophysical mechanism of antimicrobial peptides and petidomimetics so as to be better able to modify and design new effective antimicrobial agents.

The candidate will perform systematic studies of the interactions between model biomembranes (liposomes, supported bilayers) and antimicrobial peptides and investigate their effect on structure, dynamics and transport using manly X-ray and neutron scattering techniques. The main methods will be small angle neutron/X-ray scattering (SAXS/SANS), neutron/X-ray reflectometry including advanced data modeling. Complementary techniques are mainly light scattering, single ion conductivity (BLM) and calorimetry.

The PhD work will be done in close collaboration with Roskilde University and University of Copenhagen who will design, synthesize and perform biological characterization of the antimicrobial compounds.

Starting date as soon as possible. No one can be appointed for more than one fixed-term period at the same institution.

Salary:

The employment will be provided by the University of Oslo:
Position code 1017, Pay grade: 50 – 57 (NOK 432 700 – 489 300 per year) depending on qualifications and seniority.

Requested Profile

Requirements/qualifications:

Applicants must hold a MSc degree in relevant fields of chemistry, pharmacy or physics, preferably with experience from the fields of physical chemistry, biophysics, soft matter science or similar. The candidate must qualify for admission to the PhD-program at the Faculty of Mathematics and Natural Sciences at the University of Oslo. Preference will be given to a candidate with previous experience within soft matter and/or biophysical chemistry and/or knowledge within X-ray/neutron scattering techniques and related data modeling.

The Faculty of Mathematics and Natural Sciences has a strategic ambition of being a leading research faculty. Candidates for these fellowships will be selected in accordance with this, and expected to be in the upper segment of their class with respect to academic credentials.

Candidates without a Master’s degree have until 15 April, 2017 to complete the final exam.

The purpose of the fellowship is research training leading to the successful completion of a PhD degree.

The fellowship requires admission to the PhD program at the Faculty of Mathematics and Natural Sciences. The application to the PhD program must be submitted to the department no later than two months after taking up the position. For more information see:

http://www.uio.no/english/research/phd/

http://www.mn.uio.no/english/research/phd/

A good command of English is required.

http://www.mn.uio.no/english/research/phd/application/application.html

Contact
Name

Associate Professor Reidar Lund

Website
How to Apply

The application must include:

  • Application letter
  • CV (summarizing education, positions and academic work – scientific publications)
  • Copies of educational certificates, transcript of records and letters of recommendation
  • Documentation of English proficiency
  • List of publications and/or academic work that the applicant wishes to be considered by the evaluation committee
  • Names and contact details of 2-3 references (name, relation to candidate, e-mail and telephone number)

Foreign applicants are advised to attach an explanation of their University’s grading system. Please remember that all documents should be in English or a Scandinavian language.

Deadline
17. February 2017
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