[Neutron] PhD position at ILL - Modular protein assemblies

Maria Sunnerhagen marsu at ifm.liu.se
Wed Oct 5 17:32:53 CEST 2016

PhD position at ILL, Grenoble and LiU, Sweden - Modular Protein Assemblies in Transcriptional Regulation

Modularity is fundamental to the design of living systems. At the molecular level, proteins are made up of functional domains that perform the highly coordinated, specific binding interactions and associations that accomplish everything from genetic replication and transcription to physical movement. With a SANS focus, but also using data from SAXS, NMR, crystallography and modelling, this project will provide insight into the molecular mechanism of physiological-to-pathological switches that are controlled by modular proteins, and will thus advance both structural biology and molecular medicine. Specifically, we aim to resolve in molecular detail the multimodular regulation mechanisms of the TRIM21 E3 ligase and the MexR efflux repressor, both representing disease-affiliated protein families. While the successful applicant will focus on neutron scattering and modelling together with protein biophysics, the project includes active collaborations with medically active researchers.
The PhD project, totalling four years, will be located in Grenoble (France) at the ILL (three years), and at the University of Linköping (LiU), Sweden (one year), in close collaboration with Karolinska Institute, Stockholm. The successful candidate will be employed with a gross salary of around 2350 €/month, together with other benefits depending on the student’s social status (for more details see: http://www.ill.eu/science-technology/phd-students/phd-recruitment/phd-work-at-the-ill/). A team of experts, including Prof Maria Sunnerhagen and Dr Björn Wallner (Linköping University), Prof Marie Wahren-Herlenius (Karolinska Institute), Dr Frank Gabel (ESRF & ILL) and Dr Anne Martel (ILL), will supervise the work of the PhD student; Prof Jill Trewhella (U Sydney) will be affiliated as mentor. Applicants should have a degree in a relevant chemical, biophysical or biological discipline. Academic knowledge of condensed matter physics will be appreciated. 

The recruitment process is still open. Please contact Dr Maria Sunnerhagen (maria.sunnerhagen at liu.se) to apply! 


Maria Sunnerhagen, Professor of Structural Biology
Department of Physics, Chemistry and Biology, IFM, Linköping University, SE-581 83 Linköping
Phone: +46-13-28 66 82, E-mail: maria.sunnerhagen at liu.se 
Visiting adress: Campus Valla B-house, entrance 23, Room 221:199
Visit us at: www.liu.se

-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://neutronsources.org/pipermail/neutron/attachments/20161005/7b6e6ff4/attachment-0001.html>
-------------- next part --------------
A non-text attachment was scrubbed...
Name: liu_signatur_sv.png
Type: image/png
Size: 17288 bytes
Desc: not available
URL: <http://neutronsources.org/pipermail/neutron/attachments/20161005/7b6e6ff4/attachment-0001.png>

More information about the Neutron mailing list