Nuclear Physics Institute (ASCR), public research institution, conducts research in a broad field of nuclear physics, experimental as well as theoretical. The properties of nuclear matter under the heavy ion collisions at high and intermediate energies, nuclear reactions important for astrophysics or nuclear energetics, beta decays of atomic nuclei including the problem of neutrino masses are especially studied. The nuclear theory is oriented to nuclear structure, hypernuclei, interactions of elementary particles with nuclei, mesonic degrees of freedom in nuclei. Selected problems of theoretical subnuclear physics and mathematical physics are studied. Neutron scattering is used mainly in the solid state physics and material research. A large complex of nuclear analytical methods based on charged particles and neutrons beams is used in the interdisciplinary research in collaboration with external specialists in chemistry, ecology, medicine, archaeology etc. The dosimetry of ionizing radiation is oriented to the measurements of environmental and professional expositions, metrology, and biophysical aspects as DNA radiation damages. The research and development of radiopharmaceuticals, especially short lived positron emitters for the positron emission tomography (PET), is performed at the Institute. The physics for perspective methods of nuclear energetics like accelerator driven transmutation of nuclear waste is studied.